Caution urged in fluoroquinolone antibiotic prescribing

REPORTS of rare disabling and potentially irreversible adverse reactions associated with fluoroquinolone antibiotics have prompted the Medicines and Healthcare products Regulatory Agency (MHRA) to issue an alert.

The MHRA is urging prescribers and dispensers of fluoroquinolones (ciprofloxacin, levofloxacin, moxifloxacin, ofloxacin) to advise patients to stop treatment at the first signs of a serious adverse reaction, such as tendinitis or tendon rupture, muscle pain, muscle weakness, joint pain, joint swelling, peripheral neuropathy and central nervous system effects, and to contact their doctor immediately for further advice.

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